However, he left the door open for the possibility of a Zelda spinoff game to feature a female character.
This came up in an interview with Gamekult. Nintendo Everything transcribed the question and answer from French; check it out below.
GameKult: We regularly talk about the possibility to include a female character in a Zelda game for several years. Considering her important role in the story and the name of the series, can we expect to see in the future a game with Zelda as the main protagonist? If Tingle managed to have two games in his glory on DS, surely it is possible to do something, right?
Miyamoto: "We clearly talked with the team to make a game centered about Sheik, so I cannot say it is impossible to see something of the sort in the future, but in the classic games in the series, Link is the hero and that will not change. For the rest, you have to be patient and see what happens!"
"...if we have princess Zelda as the main character who fights, then what is Link going to do?" he said. "Taking into account that, and also the idea of the balance of the Triforce, we thought it best to come back to this [original] makeup."
Breath of the Wild is scheduled to launch in 2017 for Wii U and NX. For lots more on the game, check out all of GameSpot's coverage here.